| Saturday, October 24 |
|---|
| 12:00 PM ET | Pittsburgh Panthers @ 1Miami Hurricanes | ESPN | MIA -20.5 | 51.5 |
| 12:00 PM ET | 6Indiana Hoosiers @ Michigan Wolverines | Fox | IU -7 | 41.5 |
| 12:00 PM ET | 8Texas Tech Red Raiders @ Cincinnati Bearcats | FS1 | TTU -10.5 | 56.5 |
| 12:00 PM ET | 18LSU Tigers @ Auburn Tigers | ABC | LSU -8.5 | 50.5 |
| 12:00 PM ET | California Golden Bears @ 23SMU Mustangs | CW | SMU -18.5 | 53.5 |
| 12:00 PM ET | Rutgers Scarlet Knights @ 24Northwestern Wildcats | Peacock | NU -16.5 | 58.5 |
| 12:00 PM ET | West Virginia Mountaineers @ TCU Horned Frogs | ESPN2 | TCU -8.5 | 56.5 |
| 12:00 PM ET | Rice Owls @ Florida Atlantic Owls | ESPNU | FAU -10 | 54.5 |
| 12:00 PM ET | Western Michigan Broncos @ Toledo Rockets | CBSSN | TOL -3 | 45.5 |
| 1:00 PM ET | Baylor Bears @ Kansas Jayhawks | TNT | BAY -3 | 53.5 |
| 1:00 PM ET | Akron Zips @ Kent State Golden Flashes | ESPN+ | KENT -3 | 46.5 |
| 1:00 PM ET | Miami (OH) RedHawks @ Central Michigan Chippewas | ESPN+ | M-OH -2.5 | 42.5 |
| 3:00 PM ET | Oregon Ducks @ Illinois Fighting Illini | BTN | ORE -8.5 | 50.5 |
| 3:30 PM ET | 2BYU Cougars @ UCF Knights | Fox | BYU -6.5 | 43.5 |
| 3:30 PM ET | Michigan State Spartans @ 9UCLA Bruins | CBS | UCLA -14 | 44.5 |
| 3:30 PM ET | 11Tennessee Volunteers @ South Carolina Gamecocks | ESPN | SC -2.5 | 50.5 |
| 3:30 PM ET | Texas A&M Aggies @ 13Alabama Crimson Tide | ABC | ALA -14.5 | 50.5 |
| 3:30 PM ET | 15Iowa Hawkeyes @ Minnesota Golden Gophers | FS1 | IOWA -7 | 40.5 |
| 3:30 PM ET | Oklahoma Sooners @ Mississippi State Bulldogs | SEC Network | OU -3.5 | 45.5 |
| 3:30 PM ET | Boston College Eagles @ Georgia Tech Yellow Jackets | ACC Network | GT -4 | 49.5 |
| 3:30 PM ET | North Texas Mean Green @ Navy Midshipmen | CBSSN | UNT -1.5 | 61.5 |
| 3:30 PM ET | Hawai'i Rainbow Warriors @ Northern Illinois Huskies | MW+ | HAW -4.5 | 46.5 |
| 3:30 PM ET | Sacramento State Hornets @ Ball State Cardinals | ESPN+ | BALL -14 | 51.5 |
| 3:30 PM ET | Bowling Green Falcons @ Buffalo Bulls | ESPN+ | BUF -3.5 | 44.5 |
| 3:45 PM ET | Kansas State Wildcats @ Arizona State Sun Devils | ESPN2 | KSU -3.5 | 57.5 |
| 4:00 PM ET | Eastern Michigan Eagles @ Ohio Bobcats | ESPNU | OHIO -11.5 | 49.5 |
| 4:00 PM ET | UL Monroe Warhawks @ Troy Trojans | ESPN+ | TROY -15.5 | 51.5 |
| 5:00 PM ET | San José State Spartans @ Nevada Wolf Pack | MW+ | NEV -5.5 | 45.5 |
| 5:00 PM ET | Louisiana Ragin' Cajuns @ Southern Miss Golden Eagles | ESPN+ | UL -10 | 52.5 |
| 5:00 PM ET | Old Dominion Monarchs @ Louisiana Tech Bulldogs | ESPN+ | LT -12.5 | 46.5 |
| 6:00 PM ET | 21Boise State Broncos @ Washington State Cougars | USA Net | BOIS -13.5 | 51.5 |
| 6:30 PM ET | San Diego State Aztecs @ Colorado State Rams | CW | SDSU -2.5 | 60.5 |
| 7:00 PM ET | Colorado Buffaloes @ Oklahoma State Cowboys | FS1 | OKST -13.5 | 55.5 |
| 7:00 PM ET | Virginia Tech Hokies @ Clemson Tigers | ESPN | CLEM -2.5 | 49.5 |
| 7:00 PM ET | Georgia State Panthers @ Arkansas State Red Wolves | ESPN+ | GAST -2.5 | 58.5 |
| 7:30 PM ET | 7Ole Miss Rebels @ 19Texas Longhorns | ABC | TEX -3.5 | 52.5 |
| 7:30 PM ET | Vanderbilt Commodores @ 12Kentucky Wildcats | SEC Network | UK -11.5 | 50.5 |
| 7:30 PM ET | 16USC Trojans @ Wisconsin Badgers | NBC | USC -3 | 49.5 |
| 7:30 PM ET | Iowa State Cyclones @ 25Arizona Wildcats | ESPN2 | ARIZ -10 | 51.5 |
| 7:30 PM ET | Syracuse Orange @ North Carolina Tar Heels | ACC Network | UNC -8.5 | 46.5 |
| 7:30 PM ET | Utah State Aggies @ Texas State Bobcats | CBSSN | TXST -12.5 | 59.5 |
| 8:00 PM ET | UTSA Roadrunners @ Tulane Green Wave | ESPNU | UTSA -2.5 | 51.5 |
| 10:00 PM ET | North Dakota State Bison @ New Mexico Lobos | CW | UNM -4.5 | 41.5 |
| 10:15 PM ET | 14Houston Cougars @ 10Utah Utes | ESPN | UTAH -6.5 | 56.5 |
